Perequil
Brand names,
Perequil
Analogs
Perequil
Brand Names Mixture
Perequil
Chemical_Formula
C20H23NS
Perequil
RX_link
No information avaliable
Perequil
fda sheet
Perequil
msds (material safety sheet)
Perequil
Synthesis Reference
No information avaliable
Perequil
Molecular Weight
309.469 g/mol
Perequil
Melting Point
< 25 oC
Perequil
H2O Solubility
Soluble as HCl salt
Perequil
State
Liquid
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LogP
5.7
Perequil
Dosage Forms
Tablets (oral, 1 mg)
Perequil
Indication
Used for the symptomatic treatment of parkinsonism.
Perequil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Perequil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Perequil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Perequil
Patient Information
Perequil
Organisms Affected
Humans and other mammals