Gagexyl
Brand names,
Gagexyl
Analogs
Gagexyl
Brand Names Mixture
Gagexyl
Chemical_Formula
C20H23NS
Gagexyl
RX_link
No information avaliable
Gagexyl
fda sheet
Gagexyl
msds (material safety sheet)
Gagexyl
Synthesis Reference
No information avaliable
Gagexyl
Molecular Weight
309.469 g/mol
Gagexyl
Melting Point
< 25 oC
Gagexyl
H2O Solubility
Soluble as HCl salt
Gagexyl
State
Liquid
Gagexyl
LogP
5.7
Gagexyl
Dosage Forms
Tablets (oral, 1 mg)
Gagexyl
Indication
Used for the symptomatic treatment of parkinsonism.
Gagexyl
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Gagexyl
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Gagexyl
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Gagexyl
Patient Information
Gagexyl
Organisms Affected
Humans and other mammals