Epikur
Brand names,
Epikur
Analogs
Epikur
Brand Names Mixture
Epikur
Chemical_Formula
C20H23NS
Epikur
RX_link
No information avaliable
Epikur
fda sheet
Epikur
msds (material safety sheet)
Epikur
Synthesis Reference
No information avaliable
Epikur
Molecular Weight
309.469 g/mol
Epikur
Melting Point
< 25 oC
Epikur
H2O Solubility
Soluble as HCl salt
Epikur
State
Liquid
Epikur
LogP
5.7
Epikur
Dosage Forms
Tablets (oral, 1 mg)
Epikur
Indication
Used for the symptomatic treatment of parkinsonism.
Epikur
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Epikur
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Epikur
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Epikur
Patient Information
Epikur
Organisms Affected
Humans and other mammals