Sedanil
Brand names,
Sedanil
Analogs
Sedanil
Brand Names Mixture
Sedanil
Chemical_Formula
C20H23NS
Sedanil
RX_link
No information avaliable
Sedanil
fda sheet
Sedanil
msds (material safety sheet)
Sedanil
Synthesis Reference
No information avaliable
Sedanil
Molecular Weight
309.469 g/mol
Sedanil
Melting Point
< 25 oC
Sedanil
H2O Solubility
Soluble as HCl salt
Sedanil
State
Liquid
Sedanil
LogP
5.7
Sedanil
Dosage Forms
Tablets (oral, 1 mg)
Sedanil
Indication
Used for the symptomatic treatment of parkinsonism.
Sedanil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Sedanil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Sedanil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Sedanil
Patient Information
Sedanil
Organisms Affected
Humans and other mammals