Metractyl
Brand names,
Metractyl
Analogs
Metractyl
Brand Names Mixture
Metractyl
Chemical_Formula
C20H23NS
Metractyl
RX_link
No information avaliable
Metractyl
fda sheet
Metractyl
msds (material safety sheet)
Metractyl
Synthesis Reference
No information avaliable
Metractyl
Molecular Weight
309.469 g/mol
Metractyl
Melting Point
< 25 oC
Metractyl
H2O Solubility
Soluble as HCl salt
Metractyl
State
Liquid
Metractyl
LogP
5.7
Metractyl
Dosage Forms
Tablets (oral, 1 mg)
Metractyl
Indication
Used for the symptomatic treatment of parkinsonism.
Metractyl
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Metractyl
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Metractyl
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Metractyl
Patient Information
Metractyl
Organisms Affected
Humans and other mammals