Kesso-Bamate
Brand names,
Kesso-Bamate
Analogs
Kesso-Bamate
Brand Names Mixture
Kesso-Bamate
Chemical_Formula
C20H23NS
Kesso-Bamate
RX_link
No information avaliable
Kesso-Bamate
fda sheet
Kesso-Bamate
msds (material safety sheet)
Kesso-Bamate
Synthesis Reference
No information avaliable
Kesso-Bamate
Molecular Weight
309.469 g/mol
Kesso-Bamate
Melting Point
< 25 oC
Kesso-Bamate
H2O Solubility
Soluble as HCl salt
Kesso-Bamate
State
Liquid
Kesso-Bamate
LogP
5.7
Kesso-Bamate
Dosage Forms
Tablets (oral, 1 mg)
Kesso-Bamate
Indication
Used for the symptomatic treatment of parkinsonism.
Kesso-Bamate
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Kesso-Bamate
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Kesso-Bamate
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Kesso-Bamate
Patient Information
Kesso-Bamate
Organisms Affected
Humans and other mammals