Wyseals
Brand names,
Wyseals
Analogs
Wyseals
Brand Names Mixture
Wyseals
Chemical_Formula
C20H23NS
Wyseals
RX_link
No information avaliable
Wyseals
fda sheet
Wyseals
msds (material safety sheet)
Wyseals
Synthesis Reference
No information avaliable
Wyseals
Molecular Weight
309.469 g/mol
Wyseals
Melting Point
< 25 oC
Wyseals
H2O Solubility
Soluble as HCl salt
Wyseals
State
Liquid
Wyseals
LogP
5.7
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Dosage Forms
Tablets (oral, 1 mg)
Wyseals
Indication
Used for the symptomatic treatment of parkinsonism.
Wyseals
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Wyseals
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Wyseals
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Wyseals
Patient Information
Wyseals
Organisms Affected
Humans and other mammals