Erina
Brand names,
Erina
Analogs
Erina
Brand Names Mixture
Erina
Chemical_Formula
C20H23NS
Erina
RX_link
No information avaliable
Erina
fda sheet
Erina
msds (material safety sheet)
Erina
Synthesis Reference
No information avaliable
Erina
Molecular Weight
309.469 g/mol
Erina
Melting Point
< 25 oC
Erina
H2O Solubility
Soluble as HCl salt
Erina
State
Liquid
Erina
LogP
5.7
Erina
Dosage Forms
Tablets (oral, 1 mg)
Erina
Indication
Used for the symptomatic treatment of parkinsonism.
Erina
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Erina
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Erina
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Erina
Patient Information
Erina
Organisms Affected
Humans and other mammals