Mepronil
Brand names,
Mepronil
Analogs
Mepronil
Brand Names Mixture
Mepronil
Chemical_Formula
C20H23NS
Mepronil
RX_link
No information avaliable
Mepronil
fda sheet
Mepronil
msds (material safety sheet)
Mepronil
Synthesis Reference
No information avaliable
Mepronil
Molecular Weight
309.469 g/mol
Mepronil
Melting Point
< 25 oC
Mepronil
H2O Solubility
Soluble as HCl salt
Mepronil
State
Liquid
Mepronil
LogP
5.7
Mepronil
Dosage Forms
Tablets (oral, 1 mg)
Mepronil
Indication
Used for the symptomatic treatment of parkinsonism.
Mepronil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Mepronil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Mepronil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Mepronil
Patient Information
Mepronil
Organisms Affected
Humans and other mammals