Nervonus
Brand names,
Nervonus
Analogs
Nervonus
Brand Names Mixture
Nervonus
Chemical_Formula
C20H23NS
Nervonus
RX_link
No information avaliable
Nervonus
fda sheet
Nervonus
msds (material safety sheet)
Nervonus
Synthesis Reference
No information avaliable
Nervonus
Molecular Weight
309.469 g/mol
Nervonus
Melting Point
< 25 oC
Nervonus
H2O Solubility
Soluble as HCl salt
Nervonus
State
Liquid
Nervonus
LogP
5.7
Nervonus
Dosage Forms
Tablets (oral, 1 mg)
Nervonus
Indication
Used for the symptomatic treatment of parkinsonism.
Nervonus
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Nervonus
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Nervonus
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Nervonus
Patient Information
Nervonus
Organisms Affected
Humans and other mammals