Meprozine
Brand names,
Meprozine
Analogs
Meprozine
Brand Names Mixture
Meprozine
Chemical_Formula
C20H23NS
Meprozine
RX_link
No information avaliable
Meprozine
fda sheet
Meprozine
msds (material safety sheet)
Meprozine
Synthesis Reference
No information avaliable
Meprozine
Molecular Weight
309.469 g/mol
Meprozine
Melting Point
< 25 oC
Meprozine
H2O Solubility
Soluble as HCl salt
Meprozine
State
Liquid
Meprozine
LogP
5.7
Meprozine
Dosage Forms
Tablets (oral, 1 mg)
Meprozine
Indication
Used for the symptomatic treatment of parkinsonism.
Meprozine
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprozine
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprozine
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprozine
Patient Information
Meprozine
Organisms Affected
Humans and other mammals