Setran
Brand names,
Setran
Analogs
Setran
Brand Names Mixture
Setran
Chemical_Formula
C20H23NS
Setran
RX_link
No information avaliable
Setran
fda sheet
Setran
msds (material safety sheet)
Setran
Synthesis Reference
No information avaliable
Setran
Molecular Weight
309.469 g/mol
Setran
Melting Point
< 25 oC
Setran
H2O Solubility
Soluble as HCl salt
Setran
State
Liquid
Setran
LogP
5.7
Setran
Dosage Forms
Tablets (oral, 1 mg)
Setran
Indication
Used for the symptomatic treatment of parkinsonism.
Setran
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Setran
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Setran
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Setran
Patient Information
Setran
Organisms Affected
Humans and other mammals