Mepro-analgesic
Brand names,
Mepro-analgesic
Analogs
Mepro-analgesic
Brand Names Mixture
Mepro-analgesic
Chemical_Formula
C20H23NS
Mepro-analgesic
RX_link
No information avaliable
Mepro-analgesic
fda sheet
Mepro-analgesic
msds (material safety sheet)
Mepro-analgesic
Synthesis Reference
No information avaliable
Mepro-analgesic
Molecular Weight
309.469 g/mol
Mepro-analgesic
Melting Point
< 25 oC
Mepro-analgesic
H2O Solubility
Soluble as HCl salt
Mepro-analgesic
State
Liquid
Mepro-analgesic
LogP
5.7
Mepro-analgesic
Dosage Forms
Tablets (oral, 1 mg)
Mepro-analgesic
Indication
Used for the symptomatic treatment of parkinsonism.
Mepro-analgesic
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Mepro-analgesic
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Mepro-analgesic
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Mepro-analgesic
Patient Information
Mepro-analgesic
Organisms Affected
Humans and other mammals