Ansietan
Brand names,
Ansietan
Analogs
Ansietan
Brand Names Mixture
Ansietan
Chemical_Formula
C20H23NS
Ansietan
RX_link
No information avaliable
Ansietan
fda sheet
Ansietan
msds (material safety sheet)
Ansietan
Synthesis Reference
No information avaliable
Ansietan
Molecular Weight
309.469 g/mol
Ansietan
Melting Point
< 25 oC
Ansietan
H2O Solubility
Soluble as HCl salt
Ansietan
State
Liquid
Ansietan
LogP
5.7
Ansietan
Dosage Forms
Tablets (oral, 1 mg)
Ansietan
Indication
Used for the symptomatic treatment of parkinsonism.
Ansietan
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Ansietan
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Ansietan
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Ansietan
Patient Information
Ansietan
Organisms Affected
Humans and other mammals