Meproten
Brand names,
Meproten
Analogs
Meproten
Brand Names Mixture
Meproten
Chemical_Formula
C20H23NS
Meproten
RX_link
No information avaliable
Meproten
fda sheet
Meproten
msds (material safety sheet)
Meproten
Synthesis Reference
No information avaliable
Meproten
Molecular Weight
309.469 g/mol
Meproten
Melting Point
< 25 oC
Meproten
H2O Solubility
Soluble as HCl salt
Meproten
State
Liquid
Meproten
LogP
5.7
Meproten
Dosage Forms
Tablets (oral, 1 mg)
Meproten
Indication
Used for the symptomatic treatment of parkinsonism.
Meproten
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meproten
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meproten
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meproten
Patient Information
Meproten
Organisms Affected
Humans and other mammals