Dapaz
Brand names,
Dapaz
Analogs
Dapaz
Brand Names Mixture
Dapaz
Chemical_Formula
C20H23NS
Dapaz
RX_link
No information avaliable
Dapaz
fda sheet
Dapaz
msds (material safety sheet)
Dapaz
Synthesis Reference
No information avaliable
Dapaz
Molecular Weight
309.469 g/mol
Dapaz
Melting Point
< 25 oC
Dapaz
H2O Solubility
Soluble as HCl salt
Dapaz
State
Liquid
Dapaz
LogP
5.7
Dapaz
Dosage Forms
Tablets (oral, 1 mg)
Dapaz
Indication
Used for the symptomatic treatment of parkinsonism.
Dapaz
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Dapaz
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Dapaz
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Dapaz
Patient Information
Dapaz
Organisms Affected
Humans and other mammals