Biobamate
Brand names,
Biobamate
Analogs
Biobamate
Brand Names Mixture
Biobamate
Chemical_Formula
C20H23NS
Biobamate
RX_link
No information avaliable
Biobamate
fda sheet
Biobamate
msds (material safety sheet)
Biobamate
Synthesis Reference
No information avaliable
Biobamate
Molecular Weight
309.469 g/mol
Biobamate
Melting Point
< 25 oC
Biobamate
H2O Solubility
Soluble as HCl salt
Biobamate
State
Liquid
Biobamate
LogP
5.7
Biobamate
Dosage Forms
Tablets (oral, 1 mg)
Biobamate
Indication
Used for the symptomatic treatment of parkinsonism.
Biobamate
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Biobamate
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Biobamate
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Biobamate
Patient Information
Biobamate
Organisms Affected
Humans and other mammals