Andaxin
Brand names,
Andaxin
Analogs
Andaxin
Brand Names Mixture
Andaxin
Chemical_Formula
C20H23NS
Andaxin
RX_link
No information avaliable
Andaxin
fda sheet
Andaxin
msds (material safety sheet)
Andaxin
Synthesis Reference
No information avaliable
Andaxin
Molecular Weight
309.469 g/mol
Andaxin
Melting Point
< 25 oC
Andaxin
H2O Solubility
Soluble as HCl salt
Andaxin
State
Liquid
Andaxin
LogP
5.7
Andaxin
Dosage Forms
Tablets (oral, 1 mg)
Andaxin
Indication
Used for the symptomatic treatment of parkinsonism.
Andaxin
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Andaxin
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Andaxin
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Andaxin
Patient Information
Andaxin
Organisms Affected
Humans and other mammals