Vistabamate
Brand names,
Vistabamate
Analogs
Vistabamate
Brand Names Mixture
Vistabamate
Chemical_Formula
C20H23NS
Vistabamate
RX_link
No information avaliable
Vistabamate
fda sheet
Vistabamate
msds (material safety sheet)
Vistabamate
Synthesis Reference
No information avaliable
Vistabamate
Molecular Weight
309.469 g/mol
Vistabamate
Melting Point
< 25 oC
Vistabamate
H2O Solubility
Soluble as HCl salt
Vistabamate
State
Liquid
Vistabamate
LogP
5.7
Vistabamate
Dosage Forms
Tablets (oral, 1 mg)
Vistabamate
Indication
Used for the symptomatic treatment of parkinsonism.
Vistabamate
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Vistabamate
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Vistabamate
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Vistabamate
Patient Information
Vistabamate
Organisms Affected
Humans and other mammals