Quivet
Brand names,
Quivet
Analogs
Quivet
Brand Names Mixture
Quivet
Chemical_Formula
C20H23NS
Quivet
RX_link
No information avaliable
Quivet
fda sheet
Quivet
msds (material safety sheet)
Quivet
Synthesis Reference
No information avaliable
Quivet
Molecular Weight
309.469 g/mol
Quivet
Melting Point
< 25 oC
Quivet
H2O Solubility
Soluble as HCl salt
Quivet
State
Liquid
Quivet
LogP
5.7
Quivet
Dosage Forms
Tablets (oral, 1 mg)
Quivet
Indication
Used for the symptomatic treatment of parkinsonism.
Quivet
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Quivet
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Quivet
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Quivet
Patient Information
Quivet
Organisms Affected
Humans and other mammals