Promate

Promate Brand names, Promate Analogs

Promate Brand Names Mixture

No information avaliable

Promate Chemical_Formula

C₂₀H₂₃NS

Promate RX_link

No information avaliable

Promate fda sheet

Promate msds (material safety sheet)

Promate Synthesis Reference

No information avaliable

Promate Molecular Weight

309.469 g/mol

Promate Melting Point

< 25 ^oC

Promate H₂O Solubility

Soluble as HCl salt

Promate State

Liquid

Promate LogP

5.7

Promate Dosage Forms

Tablets (oral, 1 mg)

Promate Indication

Used for the symptomatic treatment of parkinsonism.

Promate Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Promate Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Promate side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Promate Patient Information

Promate Organisms Affected

Humans and other mammals