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Mepranil Brand names, Mepranil Analogs

Mepranil Brand Names Mixture

  • No information avaliable

Mepranil Chemical_Formula


Mepranil RX_link

No information avaliable

Mepranil fda sheet

Mepranil msds (material safety sheet)

Mepranil Synthesis Reference

No information avaliable

Mepranil Molecular Weight

309.469 g/mol

Mepranil Melting Point

< 25 oC

Mepranil H2O Solubility

Soluble as HCl salt

Mepranil State


Mepranil LogP


Mepranil Dosage Forms

Tablets (oral, 1 mg)

Mepranil Indication

Used for the symptomatic treatment of parkinsonism.

Mepranil Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Mepranil Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Mepranil side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Mepranil Patient Information

Mepranil Organisms Affected

Humans and other mammals