Quietidon
Brand names,
Quietidon
Analogs
Quietidon
Brand Names Mixture
Quietidon
Chemical_Formula
C20H23NS
Quietidon
RX_link
No information avaliable
Quietidon
fda sheet
Quietidon
msds (material safety sheet)
Quietidon
Synthesis Reference
No information avaliable
Quietidon
Molecular Weight
309.469 g/mol
Quietidon
Melting Point
< 25 oC
Quietidon
H2O Solubility
Soluble as HCl salt
Quietidon
State
Liquid
Quietidon
LogP
5.7
Quietidon
Dosage Forms
Tablets (oral, 1 mg)
Quietidon
Indication
Used for the symptomatic treatment of parkinsonism.
Quietidon
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Quietidon
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Quietidon
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Quietidon
Patient Information
Quietidon
Organisms Affected
Humans and other mammals