Harmonin

Harmonin Brand names, Harmonin Analogs

Harmonin Brand Names Mixture

No information avaliable

Harmonin Chemical_Formula

C₂₀H₂₃NS

Harmonin RX_link

No information avaliable

Harmonin fda sheet

Harmonin msds (material safety sheet)

Harmonin Synthesis Reference

No information avaliable

Harmonin Molecular Weight

309.469 g/mol

Harmonin Melting Point

< 25 ^oC

Harmonin H₂O Solubility

Soluble as HCl salt

Harmonin State

Liquid

Harmonin LogP

5.7

Harmonin Dosage Forms

Tablets (oral, 1 mg)

Harmonin Indication

Used for the symptomatic treatment of parkinsonism.

Harmonin Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Harmonin Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Harmonin side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Harmonin Patient Information

Harmonin Organisms Affected

Humans and other mammals