Ayermate
Brand names,
Ayermate
Analogs
Ayermate
Brand Names Mixture
Ayermate
Chemical_Formula
C20H23NS
Ayermate
RX_link
No information avaliable
Ayermate
fda sheet
Ayermate
msds (material safety sheet)
Ayermate
Synthesis Reference
No information avaliable
Ayermate
Molecular Weight
309.469 g/mol
Ayermate
Melting Point
< 25 oC
Ayermate
H2O Solubility
Soluble as HCl salt
Ayermate
State
Liquid
Ayermate
LogP
5.7
Ayermate
Dosage Forms
Tablets (oral, 1 mg)
Ayermate
Indication
Used for the symptomatic treatment of parkinsonism.
Ayermate
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Ayermate
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Ayermate
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Ayermate
Patient Information
Ayermate
Organisms Affected
Humans and other mammals