Pathibamate

Pathibamate Brand names, Pathibamate Analogs

Pathibamate Brand Names Mixture

No information avaliable

Pathibamate Chemical_Formula

C₂₀H₂₃NS

Pathibamate RX_link

No information avaliable

Pathibamate fda sheet

Pathibamate msds (material safety sheet)

Pathibamate Synthesis Reference

No information avaliable

Pathibamate Molecular Weight

309.469 g/mol

Pathibamate Melting Point

< 25 ^oC

Pathibamate H₂O Solubility

Soluble as HCl salt

Pathibamate State

Liquid

Pathibamate LogP

5.7

Pathibamate Dosage Forms

Tablets (oral, 1 mg)

Pathibamate Indication

Used for the symptomatic treatment of parkinsonism.

Pathibamate Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Pathibamate Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Pathibamate side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Pathibamate Patient Information

Pathibamate Organisms Affected

Humans and other mammals