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Lepenil Brand names, Lepenil Analogs

Lepenil Brand Names Mixture

  • No information avaliable

Lepenil Chemical_Formula


Lepenil RX_link

No information avaliable

Lepenil fda sheet

Lepenil msds (material safety sheet)

Lepenil Synthesis Reference

No information avaliable

Lepenil Molecular Weight

309.469 g/mol

Lepenil Melting Point

< 25 oC

Lepenil H2O Solubility

Soluble as HCl salt

Lepenil State


Lepenil LogP


Lepenil Dosage Forms

Tablets (oral, 1 mg)

Lepenil Indication

Used for the symptomatic treatment of parkinsonism.

Lepenil Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Lepenil Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Lepenil side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Lepenil Patient Information

Lepenil Organisms Affected

Humans and other mammals