Andaksin
Brand names,
Andaksin
Analogs
Andaksin
Brand Names Mixture
Andaksin
Chemical_Formula
C20H23NS
Andaksin
RX_link
No information avaliable
Andaksin
fda sheet
Andaksin
msds (material safety sheet)
Andaksin
Synthesis Reference
No information avaliable
Andaksin
Molecular Weight
309.469 g/mol
Andaksin
Melting Point
< 25 oC
Andaksin
H2O Solubility
Soluble as HCl salt
Andaksin
State
Liquid
Andaksin
LogP
5.7
Andaksin
Dosage Forms
Tablets (oral, 1 mg)
Andaksin
Indication
Used for the symptomatic treatment of parkinsonism.
Andaksin
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Andaksin
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Andaksin
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Andaksin
Patient Information
Andaksin
Organisms Affected
Humans and other mammals