Miltrate
Brand names,
Miltrate
Analogs
Miltrate
Brand Names Mixture
Miltrate
Chemical_Formula
C20H23NS
Miltrate
RX_link
No information avaliable
Miltrate
fda sheet
Miltrate
msds (material safety sheet)
Miltrate
Synthesis Reference
No information avaliable
Miltrate
Molecular Weight
309.469 g/mol
Miltrate
Melting Point
< 25 oC
Miltrate
H2O Solubility
Soluble as HCl salt
Miltrate
State
Liquid
Miltrate
LogP
5.7
Miltrate
Dosage Forms
Tablets (oral, 1 mg)
Miltrate
Indication
Used for the symptomatic treatment of parkinsonism.
Miltrate
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Miltrate
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Miltrate
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Miltrate
Patient Information
Miltrate
Organisms Affected
Humans and other mammals