Meprospan 400
Brand names,
Meprospan 400
Analogs
Meprospan 400
Brand Names Mixture
Meprospan 400
Chemical_Formula
C20H23NS
Meprospan 400
RX_link
No information avaliable
Meprospan 400
fda sheet
Meprospan 400
msds (material safety sheet)
Meprospan 400
Synthesis Reference
No information avaliable
Meprospan 400
Molecular Weight
309.469 g/mol
Meprospan 400
Melting Point
< 25 oC
Meprospan 400
H2O Solubility
Soluble as HCl salt
Meprospan 400
State
Liquid
Meprospan 400
LogP
5.7
Meprospan 400
Dosage Forms
Tablets (oral, 1 mg)
Meprospan 400
Indication
Used for the symptomatic treatment of parkinsonism.
Meprospan 400
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprospan 400
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprospan 400
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprospan 400
Patient Information
Meprospan 400
Organisms Affected
Humans and other mammals