Meprin
Brand names,
Meprin
Analogs
Meprin
Brand Names Mixture
Meprin
Chemical_Formula
C20H23NS
Meprin
RX_link
No information avaliable
Meprin
fda sheet
Meprin
msds (material safety sheet)
Meprin
Synthesis Reference
No information avaliable
Meprin
Molecular Weight
309.469 g/mol
Meprin
Melting Point
< 25 oC
Meprin
H2O Solubility
Soluble as HCl salt
Meprin
State
Liquid
Meprin
LogP
5.7
Meprin
Dosage Forms
Tablets (oral, 1 mg)
Meprin
Indication
Used for the symptomatic treatment of parkinsonism.
Meprin
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprin
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprin
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprin
Patient Information
Meprin
Organisms Affected
Humans and other mammals