Tranquilsan
Brand names,
Tranquilsan
Analogs
Tranquilsan
Brand Names Mixture
Tranquilsan
Chemical_Formula
C20H23NS
Tranquilsan
RX_link
No information avaliable
Tranquilsan
fda sheet
Tranquilsan
msds (material safety sheet)
Tranquilsan
Synthesis Reference
No information avaliable
Tranquilsan
Molecular Weight
309.469 g/mol
Tranquilsan
Melting Point
< 25 oC
Tranquilsan
H2O Solubility
Soluble as HCl salt
Tranquilsan
State
Liquid
Tranquilsan
LogP
5.7
Tranquilsan
Dosage Forms
Tablets (oral, 1 mg)
Tranquilsan
Indication
Used for the symptomatic treatment of parkinsonism.
Tranquilsan
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Tranquilsan
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Tranquilsan
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Tranquilsan
Patient Information
Tranquilsan
Organisms Affected
Humans and other mammals