Procarbamide

Procarbamide Brand names, Procarbamide Analogs

Procarbamide Brand Names Mixture

No information avaliable

Procarbamide Chemical_Formula

C₂₀H₂₃NS

Procarbamide RX_link

No information avaliable

Procarbamide fda sheet

Procarbamide msds (material safety sheet)

Procarbamide Synthesis Reference

No information avaliable

Procarbamide Molecular Weight

309.469 g/mol

Procarbamide Melting Point

< 25 ^oC

Procarbamide H₂O Solubility

Soluble as HCl salt

Procarbamide State

Liquid

Procarbamide LogP

5.7

Procarbamide Dosage Forms

Tablets (oral, 1 mg)

Procarbamide Indication

Used for the symptomatic treatment of parkinsonism.

Procarbamide Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Procarbamide Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Procarbamide side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Procarbamide Patient Information

Procarbamide Organisms Affected

Humans and other mammals