Protran

Protran Brand names, Protran Analogs

Protran Brand Names Mixture

No information avaliable

Protran Chemical_Formula

C₂₀H₂₃NS

Protran RX_link

No information avaliable

Protran fda sheet

Protran msds (material safety sheet)

Protran Synthesis Reference

No information avaliable

Protran Molecular Weight

309.469 g/mol

Protran Melting Point

< 25 ^oC

Protran H₂O Solubility

Soluble as HCl salt

Protran State

Liquid

Protran LogP

5.7

Protran Dosage Forms

Tablets (oral, 1 mg)

Protran Indication

Used for the symptomatic treatment of parkinsonism.

Protran Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Protran Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Protran side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Protran Patient Information

Protran Organisms Affected

Humans and other mammals