Apo-Meprobamate
Brand names,
Apo-Meprobamate
Analogs
Apo-Meprobamate
Brand Names Mixture
Apo-Meprobamate
Chemical_Formula
C20H23NS
Apo-Meprobamate
RX_link
No information avaliable
Apo-Meprobamate
fda sheet
Apo-Meprobamate
msds (material safety sheet)
Apo-Meprobamate
Synthesis Reference
No information avaliable
Apo-Meprobamate
Molecular Weight
309.469 g/mol
Apo-Meprobamate
Melting Point
< 25 oC
Apo-Meprobamate
H2O Solubility
Soluble as HCl salt
Apo-Meprobamate
State
Liquid
Apo-Meprobamate
LogP
5.7
Apo-Meprobamate
Dosage Forms
Tablets (oral, 1 mg)
Apo-Meprobamate
Indication
Used for the symptomatic treatment of parkinsonism.
Apo-Meprobamate
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Apo-Meprobamate
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Apo-Meprobamate
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Apo-Meprobamate
Patient Information
Apo-Meprobamate
Organisms Affected
Humans and other mammals