Letyl
Brand names,
Letyl
Analogs
Letyl
Brand Names Mixture
Letyl
Chemical_Formula
C20H23NS
Letyl
RX_link
No information avaliable
Letyl
fda sheet
Letyl
msds (material safety sheet)
Letyl
Synthesis Reference
No information avaliable
Letyl
Molecular Weight
309.469 g/mol
Letyl
Melting Point
< 25 oC
Letyl
H2O Solubility
Soluble as HCl salt
Letyl
State
Liquid
Letyl
LogP
5.7
Letyl
Dosage Forms
Tablets (oral, 1 mg)
Letyl
Indication
Used for the symptomatic treatment of parkinsonism.
Letyl
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Letyl
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Letyl
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Letyl
Patient Information
Letyl
Organisms Affected
Humans and other mammals