Apasil

Apasil Brand names, Apasil Analogs

Apasil Brand Names Mixture

No information avaliable

Apasil Chemical_Formula

C₂₀H₂₃NS

Apasil RX_link

No information avaliable

Apasil fda sheet

Apasil msds (material safety sheet)

Apasil Synthesis Reference

No information avaliable

Apasil Molecular Weight

309.469 g/mol

Apasil Melting Point

< 25 ^oC

Apasil H₂O Solubility

Soluble as HCl salt

Apasil State

Liquid

Apasil LogP

5.7

Apasil Dosage Forms

Tablets (oral, 1 mg)

Apasil Indication

Used for the symptomatic treatment of parkinsonism.

Apasil Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Apasil Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Apasil side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Apasil Patient Information

Apasil Organisms Affected

Humans and other mammals