Deprol
Brand names,
Deprol
Analogs
Deprol
Brand Names Mixture
Deprol
Chemical_Formula
C20H23NS
Deprol
RX_link
No information avaliable
Deprol
fda sheet
Deprol
msds (material safety sheet)
Deprol
Synthesis Reference
No information avaliable
Deprol
Molecular Weight
309.469 g/mol
Deprol
Melting Point
< 25 oC
Deprol
H2O Solubility
Soluble as HCl salt
Deprol
State
Liquid
Deprol
LogP
5.7
Deprol
Dosage Forms
Tablets (oral, 1 mg)
Deprol
Indication
Used for the symptomatic treatment of parkinsonism.
Deprol
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Deprol
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Deprol
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Deprol
Patient Information
Deprol
Organisms Affected
Humans and other mammals