Mendel
Brand names,
Mendel
Analogs
Mendel
Brand Names Mixture
Mendel
Chemical_Formula
C20H23NS
Mendel
RX_link
No information avaliable
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fda sheet
Mendel
msds (material safety sheet)
Mendel
Synthesis Reference
No information avaliable
Mendel
Molecular Weight
309.469 g/mol
Mendel
Melting Point
< 25 oC
Mendel
H2O Solubility
Soluble as HCl salt
Mendel
State
Liquid
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LogP
5.7
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Dosage Forms
Tablets (oral, 1 mg)
Mendel
Indication
Used for the symptomatic treatment of parkinsonism.
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Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Mendel
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Mendel
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Mendel
Patient Information
Mendel
Organisms Affected
Humans and other mammals