Milprem-200
Brand names,
Milprem-200
Analogs
Milprem-200
Brand Names Mixture
Milprem-200
Chemical_Formula
C20H23NS
Milprem-200
RX_link
No information avaliable
Milprem-200
fda sheet
Milprem-200
msds (material safety sheet)
Milprem-200
Synthesis Reference
No information avaliable
Milprem-200
Molecular Weight
309.469 g/mol
Milprem-200
Melting Point
< 25 oC
Milprem-200
H2O Solubility
Soluble as HCl salt
Milprem-200
State
Liquid
Milprem-200
LogP
5.7
Milprem-200
Dosage Forms
Tablets (oral, 1 mg)
Milprem-200
Indication
Used for the symptomatic treatment of parkinsonism.
Milprem-200
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Milprem-200
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Milprem-200
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Milprem-200
Patient Information
Milprem-200
Organisms Affected
Humans and other mammals