Sadanyl
Brand names,
Sadanyl
Analogs
Sadanyl
Brand Names Mixture
Sadanyl
Chemical_Formula
C20H23NS
Sadanyl
RX_link
No information avaliable
Sadanyl
fda sheet
Sadanyl
msds (material safety sheet)
Sadanyl
Synthesis Reference
No information avaliable
Sadanyl
Molecular Weight
309.469 g/mol
Sadanyl
Melting Point
< 25 oC
Sadanyl
H2O Solubility
Soluble as HCl salt
Sadanyl
State
Liquid
Sadanyl
LogP
5.7
Sadanyl
Dosage Forms
Tablets (oral, 1 mg)
Sadanyl
Indication
Used for the symptomatic treatment of parkinsonism.
Sadanyl
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Sadanyl
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Sadanyl
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Sadanyl
Patient Information
Sadanyl
Organisms Affected
Humans and other mammals