Meposed
Brand names,
Meposed
Analogs
Meposed
Brand Names Mixture
Meposed
Chemical_Formula
C20H23NS
Meposed
RX_link
No information avaliable
Meposed
fda sheet
Meposed
msds (material safety sheet)
Meposed
Synthesis Reference
No information avaliable
Meposed
Molecular Weight
309.469 g/mol
Meposed
Melting Point
< 25 oC
Meposed
H2O Solubility
Soluble as HCl salt
Meposed
State
Liquid
Meposed
LogP
5.7
Meposed
Dosage Forms
Tablets (oral, 1 mg)
Meposed
Indication
Used for the symptomatic treatment of parkinsonism.
Meposed
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meposed
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meposed
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meposed
Patient Information
Meposed
Organisms Affected
Humans and other mammals