Tranmep
Brand names,
Tranmep
Analogs
Tranmep
Brand Names Mixture
Tranmep
Chemical_Formula
C20H23NS
Tranmep
RX_link
No information avaliable
Tranmep
fda sheet
Tranmep
msds (material safety sheet)
Tranmep
Synthesis Reference
No information avaliable
Tranmep
Molecular Weight
309.469 g/mol
Tranmep
Melting Point
< 25 oC
Tranmep
H2O Solubility
Soluble as HCl salt
Tranmep
State
Liquid
Tranmep
LogP
5.7
Tranmep
Dosage Forms
Tablets (oral, 1 mg)
Tranmep
Indication
Used for the symptomatic treatment of parkinsonism.
Tranmep
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Tranmep
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Tranmep
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Tranmep
Patient Information
Tranmep
Organisms Affected
Humans and other mammals