Restenil
Brand names,
Restenil
Analogs
Restenil
Brand Names Mixture
Restenil
Chemical_Formula
C20H23NS
Restenil
RX_link
No information avaliable
Restenil
fda sheet
Restenil
msds (material safety sheet)
Restenil
Synthesis Reference
No information avaliable
Restenil
Molecular Weight
309.469 g/mol
Restenil
Melting Point
< 25 oC
Restenil
H2O Solubility
Soluble as HCl salt
Restenil
State
Liquid
Restenil
LogP
5.7
Restenil
Dosage Forms
Tablets (oral, 1 mg)
Restenil
Indication
Used for the symptomatic treatment of parkinsonism.
Restenil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Restenil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Restenil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Restenil
Patient Information
Restenil
Organisms Affected
Humans and other mammals