Amosene

Amosene Brand names, Amosene Analogs

Amosene Brand Names Mixture

No information avaliable

Amosene Chemical_Formula

C₂₀H₂₃NS

Amosene RX_link

No information avaliable

Amosene fda sheet

Amosene msds (material safety sheet)

Amosene Synthesis Reference

No information avaliable

Amosene Molecular Weight

309.469 g/mol

Amosene Melting Point

< 25 ^oC

Amosene H₂O Solubility

Soluble as HCl salt

Amosene State

Liquid

Amosene LogP

5.7

Amosene Dosage Forms

Tablets (oral, 1 mg)

Amosene Indication

Used for the symptomatic treatment of parkinsonism.

Amosene Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Amosene Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Amosene side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Amosene Patient Information

Amosene Organisms Affected

Humans and other mammals