Meprovanmeprozine
Brand names,
Meprovanmeprozine
Analogs
Meprovanmeprozine
Brand Names Mixture
Meprovanmeprozine
Chemical_Formula
C20H23NS
Meprovanmeprozine
RX_link
No information avaliable
Meprovanmeprozine
fda sheet
Meprovanmeprozine
msds (material safety sheet)
Meprovanmeprozine
Synthesis Reference
No information avaliable
Meprovanmeprozine
Molecular Weight
309.469 g/mol
Meprovanmeprozine
Melting Point
< 25 oC
Meprovanmeprozine
H2O Solubility
Soluble as HCl salt
Meprovanmeprozine
State
Liquid
Meprovanmeprozine
LogP
5.7
Meprovanmeprozine
Dosage Forms
Tablets (oral, 1 mg)
Meprovanmeprozine
Indication
Used for the symptomatic treatment of parkinsonism.
Meprovanmeprozine
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprovanmeprozine
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprovanmeprozine
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprovanmeprozine
Patient Information
Meprovanmeprozine
Organisms Affected
Humans and other mammals