Selene
Brand names,
Selene
Analogs
Selene
Brand Names Mixture
Selene
Chemical_Formula
C20H23NS
Selene
RX_link
No information avaliable
Selene
fda sheet
Selene
msds (material safety sheet)
Selene
Synthesis Reference
No information avaliable
Selene
Molecular Weight
309.469 g/mol
Selene
Melting Point
< 25 oC
Selene
H2O Solubility
Soluble as HCl salt
Selene
State
Liquid
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LogP
5.7
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Dosage Forms
Tablets (oral, 1 mg)
Selene
Indication
Used for the symptomatic treatment of parkinsonism.
Selene
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Selene
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Selene
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Selene
Patient Information
Selene
Organisms Affected
Humans and other mammals