Scolazil
Brand names,
Scolazil
Analogs
Scolazil
Brand Names Mixture
Scolazil
Chemical_Formula
C20H23NS
Scolazil
RX_link
No information avaliable
Scolazil
fda sheet
Scolazil
msds (material safety sheet)
Scolazil
Synthesis Reference
No information avaliable
Scolazil
Molecular Weight
309.469 g/mol
Scolazil
Melting Point
< 25 oC
Scolazil
H2O Solubility
Soluble as HCl salt
Scolazil
State
Liquid
Scolazil
LogP
5.7
Scolazil
Dosage Forms
Tablets (oral, 1 mg)
Scolazil
Indication
Used for the symptomatic treatment of parkinsonism.
Scolazil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Scolazil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Scolazil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Scolazil
Patient Information
Scolazil
Organisms Affected
Humans and other mammals