Wardamate
Brand names,
Wardamate
Analogs
Wardamate
Brand Names Mixture
Wardamate
Chemical_Formula
C20H23NS
Wardamate
RX_link
No information avaliable
Wardamate
fda sheet
Wardamate
msds (material safety sheet)
Wardamate
Synthesis Reference
No information avaliable
Wardamate
Molecular Weight
309.469 g/mol
Wardamate
Melting Point
< 25 oC
Wardamate
H2O Solubility
Soluble as HCl salt
Wardamate
State
Liquid
Wardamate
LogP
5.7
Wardamate
Dosage Forms
Tablets (oral, 1 mg)
Wardamate
Indication
Used for the symptomatic treatment of parkinsonism.
Wardamate
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Wardamate
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Wardamate
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Wardamate
Patient Information
Wardamate
Organisms Affected
Humans and other mammals