Panediol
Brand names,
Panediol
Analogs
Panediol
Brand Names Mixture
Panediol
Chemical_Formula
C20H23NS
Panediol
RX_link
No information avaliable
Panediol
fda sheet
Panediol
msds (material safety sheet)
Panediol
Synthesis Reference
No information avaliable
Panediol
Molecular Weight
309.469 g/mol
Panediol
Melting Point
< 25 oC
Panediol
H2O Solubility
Soluble as HCl salt
Panediol
State
Liquid
Panediol
LogP
5.7
Panediol
Dosage Forms
Tablets (oral, 1 mg)
Panediol
Indication
Used for the symptomatic treatment of parkinsonism.
Panediol
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Panediol
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Panediol
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Panediol
Patient Information
Panediol
Organisms Affected
Humans and other mammals